Rheumatoid arthritis (RA) is an inflammation of the joints that affects nearly 1% of the world's adult population. It is determined by symmetrical polyarticular inflammation of the synovium, small joints of the hands (MCP and PIP), wrists, and feet.
This inflammation is pain and stiffness and can cause progressive joint destruction leading to deformity and dysfunction. Destruction of the associated organs also plays a role in severe damage.
In addition, chronic inflammation secondary to RA can also lead to an increased risk of heart problems and changes in bone metabolism. In the case of emergency, you can also get medical advice for your problem.
These newer drugs have shown greater promise for improving disease outcomes, but it is also important to note that they are associated with marked side effects that can lead to long-term treatment challenges and preoperative difficulties.
Image Source: Google
Inflammation and consistent alignment of the synovial joints will be a sign of RA. Why your immune system is tempted to attack and destroy is still unknown, but great steps have been taken to find out how.
Inflammation of human synovial tissue involves interactions between macrophages, T and B lymphocytes, synovial fibroblasts, and other cells of the inflamed synovial cell, which may include fat cells, dendritic cells, and plasma cells.
One patient with RA responded naturally and systemically. According to one study, the problem that stimulates osteoclasts, leading to increased bone loss, is supplied locally by inflammatory and fibroblastic pannus cells.